[Influence of HIV infection on hepatitis B virus infection in homosexual patients] NLM AIDSLINE Important note: Information in this article was accurate in 1990. The state of the art may have changed since the publication date.

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[Influence of HIV infection on hepatitis B virus infection in homosexual patients]

Gastroenterol Clin Biol. 1989 Aug-Sep;13(8-9):696-700. Unique Identifier : AIDSLINE MED/90033966
Favre O; Heyraud JP; Chossegros P; Retornaz G; Ouzan D; Neyrat M; Trepo C; Unite d'Hepatologie, Hotel-Dieu, Lyon.

Abstract: Clinical expression and outcome of hepatis B virus infections associated with human immunodeficiency virus infection (without AIDS) were studied in 17 homosexuals during 23 months. In an attempt to distinguish the respective impacts of homosexuality from that of human immuno-deficiency virus, patient were compared with a population of homosexual males infected by hepatitis B virus alone. The ratio of biochemical evidence of liver cell necrosis (ALAT)/viral replication (DNAp) was significatively decreased (p less than 0.01), despite evidence of severe histological damage in some cases. Two-thirds of patients with HBV replication tolerated HBV infection at the end of follow-up. This tolerance was significatively more common than in homosexuals infected by HBV alone (p less than 0.01), and did not appear to be related to decreased T4 cell count but seemed to correlate with the existence of the AIDS related complex.
Keywords: Adult Comparative Study English Abstract Follow-Up Studies Hepatitis B/*COMPLICATIONS/IMMUNOLOGY/PATHOLOGY Hepatitis B Virus/PHYSIOLOGY *Homosexuality Human HIV Infections/*COMPLICATIONS Male Middle Age Time Factors Virus Replication JOURNAL ARTICLEKWDadultcomparativestudyenglishabstractfollow-upstudieshepatitisb/KWDcomplications/immunology/pathologyhepatitisbvirus/physiologyKWDhomosexualityhumanhivinfections/KWDcomplicationsmalemiddleagetimefactorsvirusreplicationjournalarticle
900228
M9020516

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