Acute myelocytic leukemia and prior allergies. NLM AIDSLINE Important note: Information in this article was accurate in 1990. The state of the art may have changed since the publication date.

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Acute myelocytic leukemia and prior allergies.

J Clin Epidemiol. 1989;42(10):995-1001. Unique Identifier : AIDSLINE MED/90039413
Severson RK; Davis S; Thomas DB; Stevens RG; Heuser L; Sever LE; Division of Epidemiology, University of Minnesota, Minneapolis; 55455.

Abstract: The relationship between prior allergies and adult acute myelocytic leukemia was investigated in a population-based case-control study. Based on data from personal interviews of 98 cases and 133 controls, a history of any type of allergy was associated with a significantly decreased risk of acute myelocytic leukemia (OR = 0.35, 95% CI = 0.20-0.60). Risk declined with the total number of specific allergies reported (p less than 0.001), and was reduced in relation to a history of prior asthma, eczema and hives. The implications of these findings in relation to natural immune surveillance against developing neoplasms are discussed.
Keywords: Adult Aged Case-Control Studies Female Human Hypersensitivity/*COMPLICATIONS Leukemia, Myelocytic, Acute/EPIDEMIOLOGY/*ETIOLOGY Male Middle Age Odds Ratio Registries Risk Washington/EPIDEMIOLOGY JOURNAL ARTICLEKWDadultagedcase-controlstudiesfemalehumanhypersensitivity/KWDcomplicationsleukemia,myelocytic,acute/epidemiology/KWDetiologymalemiddleageoddsratioregistriesriskwashington/epidemiologyjournalarticle
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M9020467

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