[Seborrhea-like dermatitis in the acquired immunodeficiency syndrome. Clinical, histological, and microbiological aspects and biochemical findings]

Important note: Information in this article was accurate in 1990. The state of the art may have changed since the publication date.

[Seborrhea-like dermatitis in the acquired immunodeficiency syndrome. Clinical, histological, and microbiological aspects and biochemical findings]

G Ital Dermatol Venereol. 1989 Sep;124(9):381-8. Unique Identifier : AIDSLINE MED/90243319
Ippolito F; Passi S; Caprilli F; Di Carlo A; Morrone A; Picardo M; Valenzano L

Abstract: Seventy-six patients diagnosed as having seborrheic dermatitis (SD) were divided into two groups: group A (n = 22) otherwise healthy subjects (HIV negative) and group B (n = 54) HIV positive (ARC and AIDS cases). Thirty normal healthy subjects without SD were considered as control (group C). The three groups were subjected to the following analyses: A) skin surface lipids (SSL) and fatty acid pattern of cholesterol esters, wax esters, triglycerides and free fatty acids fractions in the affected areas; B) plasma levels of Vitamin E and fatty acids of phospholipids; C) erythrocyte glutathione peroxidase (3 cases for each group); D) frequency of Pityrosporum species in the affected areas; E) skin biopsy in the affected areas (2 cases for each group). Histological findings paralleled those reported in the Literature. SSL composition, fatty acid pattern and frequency of Pityrosporum species did not show significant variation among the 3 groups. On the contrary the blood levels of Vitamin E, polyunsaturated fatty acids of phospholipids and glutathione peroxidase were found significantly lower in A and B groups than in the controls.

Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adolescence Adult AIDS-Related Complex/*COMPLICATIONS Comparative Study Dermatitis, Seborrheic/BLOOD/*ETIOLOGY/MICROBIOLOGY/PATHOLOGY English Abstract Female Glutathione Peroxidase/BLOOD Human Lipids/ANALYSIS Malassezia/ISOLATION & PURIF Male Skin/ANALYSIS Vitamin E/BLOOD JOURNAL ARTICLE
900830
M9080711

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