Characterization of skin infiltrating cells in adult T-cell leukaemia/lymphoma (ATLL): clinical, histological and immunohistochemical studies on eight cases. NLM AIDSLINE Important note: Information in this article was accurate in 1990. The state of the art may have changed since the publication date.

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Characterization of skin infiltrating cells in adult T-cell leukaemia/lymphoma (ATLL): clinical, histological and immunohistochemical studies on eight cases.

Br J Dermatol. 1989 Nov;121(5):603-12. Unique Identifier : AIDSLINE MED/90089324
Maeda K; Takahashi M; Department of Dermatology, Sapporo Medical College, Japan.

Abstract: Eight cases of adult T-cell leukaemia/lymphoma (ATLL) with cutaneous involvement were studied. The clinical and histological features of these cases were recorded and immunohistochemistry carried out using a panel of monoclonal antibodies to T-cell differentiation antigens. Patients with ATLL showed distinct differences from patients with mycosis fungoides (MF) and Sezary syndrome (SS). Patients tended to have papulonodular and purpuric skin eruptions with pleomorphic lymphoid infiltrates, and often a degree of vasculitis. There was a high level of expression of activated T-cell antigens, CD25, CD30, CD38, T9 and Leu 8.
Keywords: Adult Aged Aged, 80 and over Antigens, CD/ANALYSIS Female Human Immunohistochemistry Leukemia-Lymphoma, T-Cell, Acute, HTLV-I-Associated/IMMUNOLOGY/ *PATHOLOGY Male Middle Age Skin Neoplasms/IMMUNOLOGY/*PATHOLOGY JOURNAL ARTICLEKWDadultagedaged,80andoverantigens,cd/analysisfemalehumanimmunohistochemistryleukemia-lymphoma,t-cell,acute,htlv-i-associated/immunology/KWDpathologymalemiddleageskinneoplasms/immunology/KWDpathologyjournalarticle
900430
M9040632

Copyright © 1990 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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