Oral hairy leukoplakia: diagnosis and management. NLM AIDSLINE Important note: Information in this article was accurate in 1989. The state of the art may have changed since the publication date.

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Oral hairy leukoplakia: diagnosis and management.

Oral Surg Oral Med Oral Pathol. 1989 Apr;67(4):396-403. Unique Identifier : AIDSLINE MED/89263146
Greenspan JS; Greenspan D; Division of Oral Biology, University of California, San Francisco; 94143-0512.

Abstract: Oral hairy leukoplakia (HL) is a remarkable lesion associated with Epstein-Barr virus (EBV) found in persons infected with the human immunodeficiency virus. The clinical and histologic features of HL are characteristic and distinctive. However, none of these features are entirely specific for HL, and we consider that the presence of EBV is required for diagnosis in questionable cases. EBV can be demonstrated by means of electron microscopy, immunocytochemistry, or molecular biologic techniques. Therapy directed toward the HL lesion is sometimes indicated; acyclovir is the current drug of preference in such cases.
Keywords: Acquired Immunodeficiency Syndrome Antiviral Agents/THERAPEUTIC USE Diagnosis, Differential Herpesvirus 4, Human Human Leukoplakia, Oral/*DIAGNOSIS/DRUG THERAPY/PATHOLOGY Male Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Tumor Virus Infections/*DIAGNOSIS/DRUG THERAPY/PATHOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL

KWDacquiredimmunodeficiencysyndromeantiviralagents/therapeuticusediagnosis,differentialherpesvirus4,humanhumanleukoplakia,oral/KWDdiagnosis/drugtherapy/pathologymalesupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDtumorvirusinfections/KWDdiagnosis/drugtherapy/pathologyjournalarticlereviewreview,tutorial
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Copyright © 1989 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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