Unusual HPV types in oral warts in association with HIV infection. NLM AIDSLINE Important note: Information in this article was accurate in 1989. The state of the art may have changed since the publication date.

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Unusual HPV types in oral warts in association with HIV infection.

J Oral Pathol. 1988 Nov;17(9-10):482-8. Unique Identifier : AIDSLINE MED/89257844
Greenspan D; de Villiers EM; Greenspan JS; de Souza YG; zur Hausen H; Department of Stomatology, University of California, San; Francisco 94143-0512.

Abstract: Human papillomaviruses (HPV) are associated with certain oral soft tissue lesions, such as papillomas, warts, condylomata, and focal epithelial hyperplasia (FEH). HPV types 2, 6, 11, 16, and 18 have been identified in some of these oral lesions, while HPV 13 and 32 are associated with FEH. Little is known about the HPV types in oral warts of persons infected with human immunodeficiency virus (HIV). In this study, oral warts in 17 HIV-seropositive individuals were biopsied. Southern blot analyses were performed and the HPV types found were HPV 7 (7/17), 13 (1/17), 32 (1/17), and 18 (1/17). The presence of HPV type 7 is unusual in that it normally is found only in butcher's warts. There was no correlation between HPV type, histopathology, and clinical appearance of the lesions examined, except that the flat (FEH type) warts contained HPV types 13, 18 and 32 (1 of each). HIV infection appears to predispose individuals to oral infection with unusual HPV types.
Keywords: Adult Blotting, Southern DNA, Viral/ANALYSIS Human *HIV Seropositivity Mouth Diseases/*MICROBIOLOGY/PATHOLOGY Papillomavirus/*CLASSIFICATION/ISOLATION & PURIF Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Warts/*MICROBIOLOGY/PATHOLOGY JOURNAL ARTICLE

KWDadultblotting,southerndna,viral/analysishumanKWDhivseropositivitymouthdiseases/KWDmicrobiology/pathologypapillomavirus/KWDclassification/isolation&purifsupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDwarts/KWDmicrobiology/pathologyjournalarticle
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Copyright © 1989 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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