Important note: Information in this article was accurate in 1989. The state of the art may have changed since the publication date.
UNUSUAL OCCURRENCES AS CLUES TO CANCER ETIOLOGY
Unusual Occurrences as Clues to Cancer Etiology. Miller RW et al, eds. Philadelphia, Taylor and Francis, 304 p., 1988.. Unique Identifier : AIDSLINE ICDB/89657146 Anonymous; No affiliation given
Abstract:
Alert clinical observations have played an important role in providing clues to cancer etiology. The next step, epidemiologic study, helps to establish the causal relationship between specific causes and genetic and environmental factors. Laboratory research provides understanding of the mechanisms involved in both carcinogenesis and normal biology. This volume includes discussions of general principles and reports by clinicians who have made and followed through on observations that implicated certain chemicals, viruses, parasites, and ionizing radiation in carcinogenesis. The following topics are covered: rare events and cancer epidemiology; etiologic insights from cancer mapping; possibilities and limitations of investigations of cancer case clusters; vinyl chloride-induced hepatic angiosarcoma; steroid-related neoplasia in human liver; mortality of 'Yusho' patients (pts); the effects of diethylstilbestrol use during pregnancy; development of adenocarcinoma and acquired cystic disease of the kidney in hemodialysis pts; environment and malignancies of the lymphatic system; lung cancer in Japanese mustard gas workers; etiology of lung cancer at the Gejiu Tin Mine, China; radiation-induced cancer and its modifying factor among A-bomb survivors; chromosome aberrations and transforming genes in leukemic and nonleukemic pts with a history of atomic bomb exposure; malignant lymphoma in African children; X-linked lymphoproliferative syndrome and pathogenesis of Epstein-Barr virus-induced lymphomagenesis; opportunistic malignancies and AIDS; epidemiologic similarities leading to etiologic hypotheses; HTLV-I-associated myelopathy; cutaneous Ki-1 lymphoma; carcinoma of the urinary bladder associated with schistosomiasis; liver cancer in an endemic area of schistosomiasis japonica; clues to genetic mechanisms in rare cancers; chromosomes and cancer families; the familial syndrome of sarcomas and other neoplasms; dysplastic nevi; genetic models for linkage analysis of ataxia-telangiectasia; frequency of multiple primary cancers and risk factors for lung and breast cancer pts; and strategies to control cancer through genetics.
Keywords: Carcinogens Human Neoplasms/CHEMICALLY INDUCED/*ETIOLOGY/GENETICS Neoplasms, Radiation-Induced/ETIOLOGY Risk Factors Tumor Virus Infections/ETIOLOGY MONOGRAPH
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Important note: Information in this article was accurate in 1989. The state of the art may have changed since the publication date.
