Hodgkin's disease in HIV-infected patients. NLM AIDSLINE Important note: Information in this article was accurate in 1989. The state of the art may have changed since the publication date.

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Hodgkin's disease in HIV-infected patients.

Biomed Pharmacother. 1988;42(5):321-5. Unique Identifier : AIDSLINE MED/89051148
Alfonso PG; Sanudo EF; Carretero JM; Galindo RC; Altozano JG; Gomez LP; Manga GP; Servicios de Oncologia, Hospital General Gregorio Maranon; Madrid, Spain.

Abstract: Eight patients with Hodgkin's disease who were seropositive to human immunodeficiency virus (HIV), 6 of them being heroin addicts and one a homosexual, were studied. Histological examination showed 4 cases of lymphocytic depletion, 2 cases of mixed cellularity, 1 nodular sclerosis, and one not classifiable. There were five cases of stage IV-B and 3 IIIs-B. The response to treatment was poor, with disproportionate cytopenia and severe infectious complications. We suggest that the atypical nature of Hodgkin's disease in patients who are seropositive for HIV might be considered to be a part of the Acquired Immunodeficiency Syndrome (AIDS).
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS/EPIDEMIOLOGY Adult Antineoplastic Agents, Combined/THERAPEUTIC USE Case Report Cyclophosphamide/ADMINISTRATION & DOSAGE Female Follow-Up Studies Heroin Dependence/COMPLICATIONS Hodgkin's Disease/*COMPLICATIONS/DRUG THERAPY/PATHOLOGY Homosexuality Human Male Neoplasm Staging Prednisone/ADMINISTRATION & DOSAGE Procarbazine/ADMINISTRATION & DOSAGE Vincristine/ADMINISTRATION & DOSAGE JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplications/epidemiologyadultantineoplasticagents,combined/therapeuticusecasereportcyclophosphamide/administration&dosagefemalefollow-upstudiesheroindependence/complicationshodgkin'sdisease/KWDcomplications/drugtherapy/pathologyhomosexualityhumanmaleneoplasmstagingprednisone/administration&dosageprocarbazine/administration&dosagevincristine/administration&dosagejournalarticle
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M8930500

Copyright © 1989 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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