Endobronchial tuberculosis in the acquired immunodeficiency syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 1989. The state of the art may have changed since the publication date.

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Endobronchial tuberculosis in the acquired immunodeficiency syndrome.

Chest. 1988 Dec;94(6):1240-4. Unique Identifier : AIDSLINE MED/89052356
Wasser LS; Shaw GW; Talavera W; Department of Medicine, Beth Israel Medical Center, New York, New; York 10011.

Abstract: Although many of the pulmonary manifestations of tuberculosis in the acquired immunodeficiency syndrome (AIDS) are well known, endobronchial involvement has not been previously described. We report the clinical, roentgenographic, and bronchoscopic features of three patients with endobronchial tuberculosis and AIDS. All of the patients had nonspecific symptoms of fever and cough; however, none exhibited the classic findings of dyspnea, wheezing, or hemoptysis. Smears of sputum were nondiagnostic. The chest x-ray film revealed mediastinal adenopathy in two patients and a lower lobe consolidation in the third; all had small ipsilateral pleural effusions. Endobronchial lesions were white or pink exophytic masses obstructing the airways, mimicking bronchogenic carcinoma. Areas of classic primary tuberculosis were seen in two of the patients. Despite ongoing clinical and roentgenographic deterioration, all patients responded well to antituberculosis medications. Given the frequency of tuberculosis in patients with AIDS and AIDS-related complex, one should maintain a high index of suspicion for involvement of the tracheobronchial tree, so as to avoid a delay in diagnosis and resultant increased morbidity and mortality.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult AIDS-Related Complex/COMPLICATIONS *Bronchi/PATHOLOGY Bronchoscopy Case Report Diagnosis, Differential Female Human Male Support, Non-U.S. Gov't Tuberculosis, Pulmonary/*COMPLICATIONS JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultaids-relatedcomplex/complicationsKWDbronchi/pathologybronchoscopycasereportdiagnosis,differentialfemalehumanmalesupport,non-uKWDsKWDgov'ttuberculosis,pulmonary/KWDcomplicationsjournalarticle
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Copyright © 1989 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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