Second infections in AIDS. A new facet to the immune mechanism. NLM AIDSLINE Important note: Information in this article was accurate in 1989. The state of the art may have changed since the publication date.

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Second infections in AIDS. A new facet to the immune mechanism.

Med Hypotheses. 1988 Dec;27(4):253-4. Unique Identifier : AIDSLINE MED/89143244
Kelly TA; Laboure College, Boston, MA 02124.

Abstract: The lack of secondary infections or the delay in their appearance in immunodeficient individuals (specifically AIDS patients) previously immunized prior to their immune deficit points to an as yet overlooked mechanism in the immune response. It is proposed that on second exposure to the antigen (Ag) there is a unique Ag presentation that alters the Ag in such a way as to induced a state of tolerance.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS/IMMUNOLOGY Antigens/ADMINISTRATION & DOSAGE Human Immune Tolerance Immunization *Models, Biological Opportunistic Infections/*COMPLICATIONS/IMMUNOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplications/immunologyantigens/administration&dosagehumanimmunetoleranceimmunizationKWDmodels,biologicalopportunisticinfections/KWDcomplications/immunologyjournalarticle
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M8960562

Copyright © 1989 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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