Flow cytometry in the diagnosis of lymphomas. NLM AIDSLINE Important note: Information in this article was accurate in 1989. The state of the art may have changed since the publication date.

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Flow cytometry in the diagnosis of lymphomas.

Cytometry Suppl. 1988;3:38-43. Unique Identifier : AIDSLINE MED/89351141
Parker JW; USC Clinical Laboratories, University of Southern California; School of Medicine, Los Angeles 90033.

Abstract: Because of recent advances in instrumentation, immunological reagents, and methods for measuring a variety of cell constituents and functions, there has been increasing interest in clinical applications of flow cytometry. Several commercially available flow cytometers and a growing list of monoclonal antibodies make it feasible for clinical laboratories to apply this technology for phenotyping leukocytes in leukemias, lymphomas, immunological disorders, transplantation, and infectious diseases. The ability to measure cell constituents such as DNA, RNA, proteins, enzymes, and hormone receptors has added to the list of applications. Use in conjunction with simultaneous phenotyping with monoclonal antibodies makes such measurements even more valuable. Phenotyping specimens from a large number of patients with lymphomas and leukemias has demonstrated the value of flow cytometry in diagnosis and patient management.
Keywords: Antibodies, Monoclonal/DIAGNOSTIC USE AIDS-Related Complex/COMPLICATIONS Flow Cytometry/METHODS Human Lymphocytes/CLASSIFICATION Lymphoma/*DIAGNOSIS/ETIOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIALKWDantibodies,monoclonal/diagnosticuseaids-relatedcomplex/complicationsflowcytometry/methodshumanlymphocytes/classificationlymphoma/KWDdiagnosis/etiologyjournalarticlereviewreview,tutorial
891230
M89C0757

Copyright © 1989 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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