Incubation time for AIDS from French transfusion-associated cases. NLM AIDSLINE Important note: Information in this article was accurate in 1989. The state of the art may have changed since the publication date.

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Incubation time for AIDS from French transfusion-associated cases.

Nature. 1989 Apr 27;338(6218):768-9. Unique Identifier : AIDSLINE MED/89238527
Costagliola D; Mary JY; Brouard N; Laporte A; Valleron AJ; INSERM U 263, Universite Paris VII, France.


Abstract: Although incubation time is a key parameter of the epidemiology of AIDS, statistical estimates based on transfusion-associated AIDS cases have, up to now, used only the single dataset provided by the AIDS program of the Centers for Disease Control (CDC) in Atlanta. Using a new dataset provided by the Direction Generale de la Sante (DGS), of the French Ministry of Health1, we estimate the mean incubation time for AIDS (median in brackets) to be 5.3 years (5.3 years) with a 90% confidence interval ranging from 4.4 to 8.9 years (4.4 to 8.8 years), when a Weibull distribution is postulated for incubation time. The previously encountered problem of very large confidence intervals (range larger than 100 years), is not observed, indicating that an accurate estimate for mean incubation time will be obtainable in the near future.
Keywords: Acquired Immunodeficiency Syndrome/EPIDEMIOLOGY/*TRANSMISSION *Blood Transfusion Comparative Study France Human Statistics Time Factors United States JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/epidemiology/KWDtransmissionKWDbloodtransfusioncomparativestudyfrancehumanstatisticstimefactorsunitedstatesjournalarticle
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Copyright © 1989 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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