Seroepidemiologic study of adult T-cell leukemia virus (ATLV) and hepatitis B virus infection in Okinawa, Japan. NLM AIDSLINE Important note: Information in this article was accurate in 1989. The state of the art may have changed since the publication date.

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Seroepidemiologic study of adult T-cell leukemia virus (ATLV) and hepatitis B virus infection in Okinawa, Japan.

Microbiol Immunol. 1988;32(9):917-23. Unique Identifier : AIDSLINE MED/89096555
Kashiwagi S; Ikematsu H; Hayashi J; Kajiyama W; Nomura H; Noguchi A; Tani S; Goto M; First Department of Internal Medicine, Faculty of Medicine,; Kyushu University, Fukuoka.

Abstract: A total of 2,283 serum samples were collected from healthy subjects in three islands of the Yaeyama district of Okinawa, Japan. These sera were tested for the presence of hepatitis B surface antigen (HBsAg), for antibody to hepatitis B core antigen (anti-HBc), and for antibody to adult T-cell leukemia-associated antigen (anti-ATLA). Correlation between hepatitis B virus infection and adult T-cell leukemia virus (ATLV) infection was determined by using the prevalence rates for three virus markers. Overall prevalence of HBsAg, anti-HBc and anti-ATLA was 6.5%, 57.4%, and 17.9%, respectively. Age-specific prevalence of anti-HBc and anti-ATLA increased with age, but that of HBsAg did not. Sex-specific prevalence of HBsAg was significantly higher in males than in females, but that of anti-ATLA was significantly higher in females than in males. Statistical analysis revealed that prevalence of anti-ATLA was significantly higher in HBsAg-positive persons and HBsAg-negative/anti-HBc-positive persons than in those negative for HBsAg and anti-HBc. These data suggest that hepatitis B virus-infected persons have a significantly higher chance of adult T-cell leukemia virus infection than those without hepatitis B virus infection in the area studied.
Keywords: Adolescence Adult Child Child, Preschool Epidemiologic Methods Female Hepatitis B/COMPLICATIONS/*EPIDEMIOLOGY/IMMUNOLOGY Hepatitis B Antibodies/ISOLATION & PURIF Hepatitis B Surface Antigens/ISOLATION & PURIF Human HTLV-BLV Antibodies/ISOLATION & PURIF HTLV-BLV Infections/COMPLICATIONS/*EPIDEMIOLOGY/IMMUNOLOGY Infant Infant, Newborn Japan Male JOURNAL ARTICLE

KWDadolescenceadultchildchild,preschoolepidemiologicmethodsfemalehepatitisb/complications/KWDepidemiology/immunologyhepatitisbantibodies/isolation&purifhepatitisbsurfaceantigens/isolation&purifhumanhtlv-blvantibodies/isolation&purifhtlv-blvinfections/complications/KWDepidemiology/immunologyinfantinfant,newbornjapanmalejournalarticle
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