The group-specific protein marker: a possible indicator of syphilis, not human immunodeficiency virus infection. NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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The group-specific protein marker: a possible indicator of syphilis, not human immunodeficiency virus infection.

Can Med Assoc J. 1988 Jun 1;138(11):1013-5. Unique Identifier : AIDSLINE MED/88223051
Pollard DR; Gill P; Day A; Bureau of Microbiology, Department of National Health and; Welfare, Ottawa, Tunney's Pasture, Ont.

Abstract: We wished to compare the frequency of group-specific (Gc) phenotypes in the general population with that in people with human immunodeficiency virus (HIV) infection to find out whether the Gc protein is a marker for susceptibility to HIV infection. We determined the phenotype frequency in 1083 randomly selected serum samples obtained from the Canadian Influenza Survey Studies and compared it with that in 263 serum samples obtained from the Federal Centre for AIDS and the Syphilis Serology Proficiency Testing Laboratory. No association between Gc phenotype and HIV status was found. However, there was a strong association between the Gc protein 1f/1f phenotype and syphilis.
Keywords: Acquired Immunodeficiency Syndrome/*BLOOD/GENETICS Adolescence Adult Aged Alleles Comparative Study Human Middle Age Phenotype Syphilis/*BLOOD/GENETICS Vitamin D-Binding Protein/*BLOOD/GENETICS JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDblood/geneticsadolescenceadultagedallelescomparativestudyhumanmiddleagephenotypesyphilis/KWDblood/geneticsvitamind-bindingprotein/KWDblood/geneticsjournalarticle
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Copyright © 1988 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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