Quantification of soluble serum HLA class I antigens in healthy volunteers and AIDS patients. NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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Quantification of soluble serum HLA class I antigens in healthy volunteers and AIDS patients.

Clin Chim Acta. 1988 May 31;174(2):207-11. Unique Identifier : AIDSLINE MED/88253836
Ferreira A; Villar ML; Alvarez Cermeno JC; Revilla Y; Garcia Rodriguez MC; Fontan G; Gonzalez-Porque P; Unidad de Immunologia, Ciudad Sanitaria La Paz, Madrid, Spain.

Abstract: A solid-phase enzyme immunoassay (ELISA) has been used to quantify human soluble Class I histocompatibility antigens in serum samples from voluntary blood donors and AIDS patients. Statistical analysis of the results showed significantly raised levels (p less than 0.01) of free HLA Class I in sera from AIDS patients (2.95 +/- 1.80 micrograms/ml) when compared with the blood donors (1.06 +/- 0.6 micrograms/ml). The assay is specific, reproducible and easy to perform. Potential uses of this determination are discussed.
Keywords: Acquired Immunodeficiency Syndrome/BLOOD/*IMMUNOLOGY *Blood Donors Comparative Study Enzyme-Linked Immunosorbent Assay Human HLA Antigens/*ANALYSIS JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/blood/KWDimmunologyKWDblooddonorscomparativestudyenzyme-linkedimmunosorbentassayhumanhlaantigens/KWDanalysisjournalarticle
881030
M88A0599

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