MOLECULAR BIOLOGY AND DIFFERENTIATION OF CANCER CELLS (ONCOGENES, GROWTH FACTORS, RECEPTORS)

Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

MOLECULAR BIOLOGY AND DIFFERENTIATION OF CANCER CELLS (ONCOGENES, GROWTH FACTORS, RECEPTORS)

Lectures and Symposia of the 14th International Cancer Congress (UICC). Volume 2. Lapis K, Eckhardt S, eds. Budapest, Akademiai Kiado, 352 p., 1987.. Unique Identifier : AIDSLINE ICDB/88641448
Anonymous; No affiliation given

Abstract: This volume is one of a series of 13 which contain selected papers presented at the 14th International Cancer Congress held in Budapest, Hungary, from August 21-27, 1986, sponsored by the UICC (International Union Against Cancer). Topics discussed include growth-related nuclear antigens and antinucleolar antibodies, conserved sequences in tumor cells, human homeo box genes and problems of post-translational phosphorylation. Another group of papers is concerned with membrane properties of cancer cells, particularly with the glycoconjugate components of the cell membrane and their possible role in cancer metastasis and tumor progression, as well as different approaches to target glycoconjugates in cancer therapy. The problem of induced differentiation is covered in several papers on a protein inducer of differentiation (D factor), differentiation inhibitory factor (I factor), chemical inducers of cell differentiation, the differentiation-associated phenotypic changes in breast cancers and cell differentiation related monoclonal antibodies. Research on oncogenes is presented in a number of papers on oncogene expression during tumor progression and induced differentiation, mechanism of action and regulation of oncogenes, antioncogenes, and the similarities between oncogene products and growth factors and growth factor receptors. The role of growth factors and their receptors in cell transformation is also discussed. Another group of papers deals with lymphoid tumors as model systems. Finally several papers are presented on the virological aspects of acquired immune deficiency syndrome in which detailed analysis of the structure and function of the human T-cell lymphotropic virus-III genome is provided.

Keywords: Acquired Immunodeficiency Syndrome/MICROBIOLOGY Animal Cell Differentiation Congresses *Growth Substances Human Molecular Biology Neoplasms/*GENETICS/PATHOLOGY *Oncogenes CONGRESS MONOGRAPH

880530
M8850482

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1988. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1988. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .