Membranoproliferative glomerulonephritis and plexogenic pulmonary arteriopathy in a homosexual man with acquired immunodeficiency syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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Membranoproliferative glomerulonephritis and plexogenic pulmonary arteriopathy in a homosexual man with acquired immunodeficiency syndrome.

Hum Pathol. 1987 Dec;18(12):1293-6. Unique Identifier : AIDSLINE MED/88056953
Kim KK; Factor SM; Department of Pathology, Albert Einstein College of Medicine,; Bronx, NY 10461.

Abstract: A 40-year-old homosexual man with the acquired immunodeficiency syndrome (AIDS) presented with dyspnea and renal insufficiency. A chest radiograph showed cardiomegaly and prominent pulmonary arteries, without alveolar infiltrates. Swan-Ganz catheterization revealed pulmonary hypertension and no evidence of left-to-right shunt. Liver function tests were normal. He was treated empirically for Pneumocystis carinii pneumonia, but he died 3 days after admission. At autopsy, membranoproliferative glomerulonephritis type III, P. carinii pneumonia, and plexogenic pulmonary arteriopathy were found. The kidney and lung were studied by electron microscopy and immunohistochemistry. Electron-dense immunoglobulin deposits were identified in glomerular capillaries and were confirmed by immunohistochemistry, but the pulmonary plexogenic lesions were negative. The combination of membranoproliferative glomerulonephritis and plexogenic pulmonary arteriopathy has not been described in AIDS to date.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Case Report Glomerulonephritis/*COMPLICATIONS/PATHOLOGY *Homosexuality Human Male *Pulmonary Artery Vascular Diseases/COMPLICATIONS/PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultcasereportglomerulonephritis/KWDcomplications/pathologyKWDhomosexualityhumanmaleKWDpulmonaryarteryvasculardiseases/complications/pathologyjournalarticle
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M8830378

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