The AHA syndrome: arthritis, hives and angioedema. NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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The AHA syndrome: arthritis, hives and angioedema.

Rheumatol Int. 1987;7(6):277-9. Unique Identifier : AIDSLINE MED/88145380
McNeil DJ; Kinsella TD; Crawford AM; Fritzler MJ; Department of Medicine, Ohio State University, Columbus 43210.

Abstract: Nine patients who have intermittently exhibited the concurrent triad of arthritis or arthralgia (A), hives or urticaria (H) and angioedema (A), in the absence of associated infection or connective-tissue disease, are reported. The ratio of women to men is 4:1, with no apparent age specificity. The duration of the disease has been up to 16 years, with an average of seven acute episodes per year, lasting up to 14 days. Upper-airway angioedema has been severe in four patients. Routine laboratory studies were normal, as were studies of complement levels, and both humoral and cellular immunity. Two samples of synovial fluid from one patient contained a marked preponderance of Ia-positive macrophages. The absence of associated infection and connective-tissue disease suggests this recurrent triad represents a distinct entity, which is designated the AHA syndrome.
Keywords: Adolescence Adult Angioneurotic Edema/*PATHOLOGY Arthritis/*PATHOLOGY Case Report Child Female Human Male Middle Age Support, Non-U.S. Gov't Syndrome Urticaria/*PATHOLOGY JOURNAL ARTICLE

KWDadolescenceadultangioneuroticedema/KWDpathologyarthritis/KWDpathologycasereportchildfemalehumanmalemiddleagesupport,non-uKWDsKWDgov'tsyndromeurticaria/KWDpathologyjournalarticle
880630
M8860477

Copyright © 1988 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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