Soluble IL-2 receptor levels in serum from blood donors seropositive for HIV. NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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Soluble IL-2 receptor levels in serum from blood donors seropositive for HIV.

J Immunol. 1988 Feb 15;140(4):1139-41. Unique Identifier : AIDSLINE MED/88140282
Prince HE; Kleinman S; Williams AE; American Red Cross Blood Services, Los Angeles/Orange Countries; Region, CA 90006.

Abstract: Serum levels of soluble IL-2R (sIL-2R) were measured in blood donors seropositive for HIV. Approximately one-half (53/101) of these seropositive donors exhibited increased serum sIL-2R levels compared with seronegative controls (n = 65). Further, a significant inverse correlation was observed between serum sIL-2R levels and CD4 cell levels in seropositive study participants. These findings suggest that increased serum sIL-2R levels in HIV infection may be linked to CD4 cell loss, and thus reflective of the stage of HIV-induced disease.
Keywords: *Blood Donors Human HIV Seropositivity/*BLOOD Leukocyte Count Receptors, Immunologic/*BLOOD Solubility Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. T-Lymphocytes, Helper-Inducer JOURNAL ARTICLE

KWDblooddonorshumanhivseropositivity/KWDbloodleukocytecountreceptors,immunologic/KWDbloodsolubilitysupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes,helper-inducerjournalarticle
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Copyright © 1988 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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