Pulmonary manifestations of the acquired immunodeficiency syndrome.

Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

Pulmonary manifestations of the acquired immunodeficiency syndrome.

Aust N Z J Med. 1987 Dec;17(6):551-6. Unique Identifier : AIDSLINE MED/88192563
Gibson PG; Bryant DH; Harkness J; Munro VF; Penny R; Cooper DA; Department of Thoracic Medicine, St. Vincent's Hospital, NSW.

Abstract: Between 1983 and 1985, 71 patients with the acquired immunodeficiency syndrome (AIDS) were evaluated. Pulmonary manifestations were present in 42 patients (59%). Pneumocystis carinii pneumonia (PCP) was the most common pulmonary manifestation, present in 32 patients (45%). Other pulmonary findings were cytomegalovirus pneumonia (one patient), Candida pneumonia (one patient), cryptococcal pneumonia (one patient), bacterial pneumonia (three patients), nonspecific pneumonitis (three patients), Kaposi's sarcoma (one patient), and non-Hodgkin's lymphoma (one patient). The presenting features of PCP were reviewed and in seven patients the chest X-ray and blood gases were normal at the time of diagnosis of PCP. Bronchoscopy was a safe and useful technique for obtaining specimens for diagnosis promptly, and a combination of samples obtained by bronchial washings/brushings and transbronchial biopsy was found to give a higher diagnostic yield than any single sample. Drug side-effects were common during therapy, requiring change of therapy in 16 patients. At one month after diagnosis 16% of patients with PCP had died. PCP is a common pulmonary manifestation in patients with AIDS which is treatable and has an initially favourable outcome.

Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Bronchoscopy/METHODS Drug Combinations/ADVERSE EFFECTS/THERAPEUTIC USE Human Lung Diseases/*COMPLICATIONS/DIAGNOSIS Lung Neoplasms/COMPLICATIONS Lymphoma, Non-Hodgkin's/COMPLICATIONS Male Middle Age Pneumonia, Pneumocystis carinii/COMPLICATIONS/DIAGNOSIS/DRUG THERAPY Sarcoma, Kaposi's/COMPLICATIONS Sulfamethoxazole/ADVERSE EFFECTS/THERAPEUTIC USE Trimethoprim/ADVERSE EFFECTS/THERAPEUTIC USE JOURNAL ARTICLE

880730
M8870440

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1988. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1988. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .