Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.
Tuberculosis and nontuberculous mycobacteriosis in patients with AIDS.
Chest. 1988 Apr;93(4):772-5. Unique Identifier : AIDSLINE MED/88166103 Fournier AM; Dickinson GM; Erdfrocht IR; Cleary T; Fischl MA; Division of General Medicine and Infectious Disease, University; of Miami School of Medicine.
Abstract:
Thirty-six patients with AIDS and culture-proven nontuberculous mycobacteriosis were compared to 20 patients with acquired immunodeficiency syndrome (AIDS) and tuberculosis with regard to clinical signs, symptoms, and diagnostic methods. Patients with nontuberculous mycobacteriosis were more often younger and homosexuals, while patients with tuberculosis were usually Haitian-American or users of intravenous drugs. A majority of patients with tuberculosis presented with fever and weight loss. These symptoms were seen in approximately 50 percent of the patients with nontuberculous mycobacteriosis. A distinct syndrome of dyspnea, chills, hemoptysis, and chest pain was seen in a significant minority of patients with nontuberculous mycobacteriosis. Lymphadenopathy was seen almost exclusively in patients with tuberculosis. Pulmonary sources (expectorated sputum or bronchoscopy specimens) were the most common source of diagnosis in both groups. Patients in both groups in whom the diagnosis was obtained from pulmonary sources frequently had negative chest x-ray films on presentation. Cavitary disease was absent from both groups.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Age Factors Bronchoscopy Comparative Study Female Haiti/ETHNOLOGY Homosexuality Human Male Mycobacterium Infections/*ETIOLOGY Mycobacterium Infections, Atypical/DIAGNOSIS/*ETIOLOGY Opportunistic Infections/*ETIOLOGY Risk Factors Sputum/MICROBIOLOGY Substance Abuse Tuberculosis, Pulmonary/DIAGNOSIS/*ETIOLOGY United States JOURNAL ARTICLE
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