[Electroretinography in AIDS retinopathy and AIDS cytomegalovirus retinitis with ganciclovir therapy] NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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[Electroretinography in AIDS retinopathy and AIDS cytomegalovirus retinitis with ganciclovir therapy]

Klin Monatsbl Augenheilkd. 1988 Jan;192(1):6-10. Unique Identifier : AIDSLINE MED/88173361
Weber U; Sundmacher R; Weiss H; Univ.-Augenklinik Dusseldorf.

Abstract: Electroretinographic (ERG) investigations were performed in three AIDS patients. The first had cotton wool-like spots in both eyes (AIDS retinopathy). The second presented with the same changes in his right eye and an acute cytomegalovirus (CMV) in his left eye. In the third patient signs of healed peripheral retinochoroiditis were found. In CMV retinitis the retinal damage demonstrated by ERG correlated well with the ophthalmoscopic findings. As the ERG improved concurrently with Ganciclovir therapy, retinal function can be monitored by means of ERG controls. In the cases of AIDS retinopathy with only a few cotton wool-like spots and with healed peripheral retinochoroiditis, pronounced changes in the ERG were seen regularly; these were most probably caused by ischemia of the inner retinal layers.
Keywords: Acquired Immunodeficiency Syndrome/*DRUG THERAPY/PHYSIOPATHOLOGY Acyclovir/*ANALOGS & DERIVATIVES/THERAPEUTIC USE Antiviral Agents/*THERAPEUTIC USE Cytomegalovirus Infections/*DRUG THERAPY/PHYSIOPATHOLOGY *Electroretinography English Abstract Human Opportunistic Infections/*DRUG THERAPY/PHYSIOPATHOLOGY Retina/PHYSIOPATHOLOGY Retinitis/*DRUG THERAPY/PHYSIOPATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDdrugtherapy/physiopathologyacyclovir/KWDanalogs&derivatives/therapeuticuseantiviralagents/KWDtherapeuticusecytomegalovirusinfections/KWDdrugtherapy/physiopathologyKWDelectroretinographyenglishabstracthumanopportunisticinfections/KWDdrugtherapy/physiopathologyretina/physiopathologyretinitis/KWDdrugtherapy/physiopathologyjournalarticle
880730
M8870097

Copyright © 1988 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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