Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.
SURGICAL CONSIDERATIONS IN THE IMMUNOCOMPROMISED CANCER PATIENT
Fundamentals of Surgical Oncology. McKenna RJ, Murphy GP, eds. New York, Macmillan Publishing Company, p. 114-40, 1986.. Unique Identifier : AIDSLINE ICDB/87638736 Bodey GP; McKenna RJ Jr; Univ. of Texas, Houston, TX
Abstract:
The immunocompromised cancer patient (pt) presents unique challenges in diagnosis and therapy. Increasingly, the surgeon is called upon to intervene in immunocompromised pts to assist in the diagnosis of infectious complications or in the therapy of the disease process. This has resulted from the lower risks of surgical procedures, improved postoperative care, the difficulty in diagnosing obscure infectious diseases, and the availability of effective therapy for many previously untreatable disorders. Consequently, the surgeon must be familiar with the special problems of these pts in order to provide optimum care. Surgical considerations in the immunocompromised cancer pt are discussed under the following headings: host factors predisposing to infection, acute abdomen, other abdominal diseases, splenectomy, perianal infections, surgical approach to aspergillosis and phycomycosis, skin infections, extravasation of vesicant drugs, CNS complications, intravascular catheters, thrombocytopenia and platelet transfusion, antibiotic therapy and hemorrhage, role of granulocyte transfusions, acquired immunodeficiency syndrome, open lung biopsy, and risks to the surgeon. (87 Refs)
Keywords: Abdomen, Acute/SURGERY Acquired Immunodeficiency Syndrome/IMMUNOLOGY Antineoplastic Agents/ADVERSE EFFECTS Bacterial Infections/IMMUNOLOGY Catheters, Indwelling Human Immune Tolerance Mycoses/IMMUNOLOGY Neoplasms/IMMUNOLOGY/*SURGERY Risk Splenectomy Surgical Wound Infection/*IMMUNOLOGY/THERAPY MONOGRAPH
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