The 3'-orf protein of human immunodeficiency virus 2 shows sequence homology with the bel3 gene of the human spumaretrovirus. NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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The 3'-orf protein of human immunodeficiency virus 2 shows sequence homology with the bel3 gene of the human spumaretrovirus.

FEBS Lett. 1987 Oct 5;222(2):286-8. Unique Identifier : AIDSLINE MED/88005169
Maurer B; Flugel RM; German Cancer Research Center, Institute of Virus Research,; Heidelberg, FRG.

Abstract: The primary amino acid sequence within a domain of 89 residues of the central part of the 3'-orf protein (p27 3'-orf) of human immunodeficiency virus (HIV-2) shares homology with the middle and carboxy-terminal portion of the bel3 gene product of human spumaretrovirus (HSRV). In addition, a limited region of the tat protein of HIV-2 but not HIV-1 shows a 28% degree of homology to the deduced protein sequence of the bel1 gene product of HSRV. Comparison between the viral sequences suggests that the 3'-orf and bel1 gene product of HSRV could serve similar functions to those in HIV-2.
Keywords: Amino Acid Sequence *Genes, Structural Human HIV/*GENETICS Molecular Sequence Data Retroviridae/*GENETICS Viral Proteins/*GENETICS JOURNAL ARTICLE

KWDaminoacidsequenceKWDgenes,structuralhumanhiv/KWDgeneticsmolecularsequencedataretroviridae/KWDgeneticsviralproteins/KWDgeneticsjournalarticle
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M8810341

Copyright © 1988 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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