Risk of AIDS for recipients of blood components from donors who subsequently developed AIDS. NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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Risk of AIDS for recipients of blood components from donors who subsequently developed AIDS.

Blood. 1987 Nov;70(5):1604-10. Unique Identifier : AIDSLINE MED/88025594
Perkins HA; Samson S; Garner J; Echenberg D; Allen JR; Cowan M; Levy JA; Irwin Memorial Blood Bank, San Francisco, CA 94118.

Abstract: Reported cases of acquired immunodeficiency syndrome (AIDS) in San Francisco as of March 31, 1986, include 92 individuals who had donated blood subsequent to 1978. Their donated blood components had been transfused into 406 different recipients. The current status of 336 of these recipients was ascertained as of April 1, 1986. Of these, 223 had died at the time of our first contact, almost all as a result of the condition for which they were transfused. Seven had developed AIDS; five of these died, two before entry into the study and three subsequently. Forty-six additional living recipients were interviewed and evaluated. Seven had the AIDS-related complex, 18 had antibody to the human immunodeficiency virus (HIV) but were otherwise healthy, and 19 had no detectable anti-HIV. Two had risk factors other than transfusion. The frequency of infection of the recipient decreased as the time interval between transfusion and the diagnosis of AIDS in the donor increased. This information should be useful when counseling patients who have been transfused with blood components from donors later found to be infected with HIV.
Keywords: Acquired Immunodeficiency Syndrome/BLOOD/EPIDEMIOLOGY/ *TRANSMISSION Adult Aged *Blood Donors Blood Transfusion/*ADVERSE EFFECTS California Child Child, Preschool Female Human Infant Male Middle Age Risk San Francisco Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/blood/epidemiology/KWDtransmissionadultagedKWDblooddonorsbloodtransfusion/KWDadverseeffectscaliforniachildchild,preschoolfemalehumaninfantmalemiddleagerisksanfranciscosupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
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M8820355

Copyright © 1988 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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