Human immunodeficiency virus-associated vitiligo: expression of autoimmunity with immunodeficiency? NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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Human immunodeficiency virus-associated vitiligo: expression of autoimmunity with immunodeficiency?

J Am Acad Dermatol. 1987 Oct;17(4):656-62. Unique Identifier : AIDSLINE MED/88033844
Duvic M; Rapini R; Hoots WK; Mansell PW; University of Texas Health Science Center at Houston, Medical; School, M.D. Anderson Hospital and Tumor Institute, Department of; Dermatology 77030.

Abstract: Persistent viral infections have been postulated to be trigger factors for the development of autoimmune disease. We report the development of vitiligo in four patients with human immunodeficiency virus (HIV)-related conditions and in one patient with hepatitis who later developed both psoriasis and acquired immunodeficiency syndrome (AIDS). Other common features were hepatitis and multiple other viral infections. Ribavirin was associated with repigmentation in one patient. Vitiligo may be an example of an autoimmune disease triggered by viral infection in a genetically predisposed host.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Autoimmune Diseases/*ETIOLOGY AIDS-Related Complex/COMPLICATIONS Case Report Child, Preschool Human Male Support, Non-U.S. Gov't Vitiligo/*ETIOLOGY/IMMUNOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultautoimmunediseases/KWDetiologyaids-relatedcomplex/complicationscasereportchild,preschoolhumanmalesupport,non-uKWDsKWDgov'tvitiligo/KWDetiology/immunologyjournalarticle
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M8820326

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