[Cerebrospinal fluid in acquired immunodeficiency syndrome. Analysis of 50 cases] NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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[Cerebrospinal fluid in acquired immunodeficiency syndrome. Analysis of 50 cases]

Arq Neuropsiquiatr. 1987 Dec;45(4):412-8. Unique Identifier : AIDSLINE MED/88208799
Spina-Franca A; Livramento JA; Machado LR; Bacheschi LA; Nobrega JP; Departamento de Neurologia, Faculdade de Medicina, Universidade; de Sao Paulo.


Abstract: Cerebrospinal fluid (CSF) was analysed in 50 AIDS patients in this investigation. CSF analysis included: pressure, aspect, colour, cytology (cell number, cytomorphology, and lymphocyte subpopulations), proteins concentration and their electrophoretic distribution, chloride and glycosis concentration, GOT and LDH activity, immunology for cysticercosis, syphilis and toxoplasmosis, bacteriology, and mycological examinations (direct, cultures, Cryptococcus neoformans antigen test). Diagnostic changes were: lymphoma cells in one patient, cryptococcosis in 10, toxoplasmosis in 4, candidiasis in 1, and syphilis in 3. Cryptococcosis occurred in association with toxoplasmosis in one patient who developed syphilis in the follow-up; oligoclonal distribution of gamma globulins occurred in this case. In another case of cryptococcosis, candidiasis appeared during the course of the disease. Changes in the CSF composition observed are discussed in order to evaluate: aspects of CSF inflammatory response in report to immunodeficiency; blood-brain barrier involvement; CNS damage; intracranial mass effects.
Keywords: Acquired Immunodeficiency Syndrome/*CEREBROSPINAL FLUID Adolescence Adult Aged Child Child, Preschool English Abstract Human Male Middle Age Opportunistic Infections/*CEREBROSPINAL FLUID Support, Non-U.S. Gov't JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcerebrospinalfluidadolescenceadultagedchildchild,preschoolenglishabstracthumanmalemiddleageopportunisticinfections/KWDcerebrospinalfluidsupport,non-uKWDsKWDgov'tjournalarticle
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M8880522


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