[Adrenal lesions in AIDS: anatomopathological study] NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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[Adrenal lesions in AIDS: anatomopathological study]

Ann Med Interne (Paris). 1987;138(8):607-9. Unique Identifier : AIDSLINE MED/88220917
Bricaire F; Marche C; Zoubi D; Perronne C; Matheron S; Rouveix E; Vittecoq D; Hopital Claude-Bernard, Paris.

Abstract: Systematic autopsy studies of 100 patients with AIDS confirmed a high incidence of adrenal lesions. Eighty eight cases were analysed, 79 men and 9 women; 57 had opportunist infection alone, 6 had Kaposi sarcomas and 30 had an association of both pathologies. The adrenal glands were normal in 19 cases and abnormal in 64 cases. One case has non-specific spongiocytic depletion and 4 were uninterpretable because of necrosis. The main adrenocortical changes were inflammatory (N = 37) or necrotic (N = 22). The commonest sites were in the adrenal medulla in the cortex or at the cortico-medullary junction. There was a high incidence of cytomegalic inclusion bodies (44 cases). In 7 cases specific lesions were observed; cryptococcus (1), toxoplasmosis (1), tuberculosis (2), Kaposi (3). Adrenal insufficiency was diagnosed before death in only 3 cases.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS/PATHOLOGY Adrenal Gland Diseases/*PATHOLOGY Adrenal Glands/*PATHOLOGY Adult Aged English Abstract Female Human Male Middle Age JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplications/pathologyadrenalglanddiseases/KWDpathologyadrenalglands/KWDpathologyadultagedenglishabstractfemalehumanmalemiddleagejournalarticle
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M8880507

Copyright © 1988 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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