[Immunological follow-up of 95 HIV seropositive drug abusers in the bresciana area] NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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[Immunological follow-up of 95 HIV seropositive drug abusers in the bresciana area]

Boll Ist Sieroter Milan. 1987;66(5):346-50. Unique Identifier : AIDSLINE MED/88209299
Cattaneo R; Franceschini F; Bettinzioli ML; Airo P; Gorla R; Stellini R; Sueri L; Cadeo GP; Carosi GP; Servizio di immunologia Clinica, Universita degli Studi di; Brescia.

Abstract: We evaluated 95 HIV seropositive drug-addicts during a follow-up period of one year. The patients were classified and reclassified at each visit, according to the criteria proposed by the Centers for Disease Control (CDC) in 1986. At the first visit the patients were classified as follows: 70 in IIa-IIIa, 23 in IIb-IIIb and 2 in group IV. a and b indicate the absence or the presence of immunological and/or hematological alterations. 1 out of 70 IIa-IIIa patients versus 8 out of 23 IIb-IIIb patients developed AIDS in one year (p less than 0.001). Only one patient belonging to IIa-IIIa groups at the first visit progressed to AIDS in one year. This patient was reclassified in subgroup b after six months. No differences were noted among patients classified in IIb (5 patients) and IIIb (4 patients) who progressed to AIDS. Taken together these data indicate that the belonging to b subgroup is a risk factor for developing AIDS and the passage through a b subgroup (II or III) is a necessary step before the appearance of clinical manifestations of AIDS.
Keywords: Acquired Immunodeficiency Syndrome/IMMUNOLOGY Adolescence Adult Antigens, Differentiation, T-Lymphocyte/ANALYSIS English Abstract Female Human *HIV Seropositivity IgA/ANALYSIS IgG/ANALYSIS IgM/ANALYSIS Male Middle Age Risk Factors Substance Abuse/*IMMUNOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/immunologyadolescenceadultantigens,differentiation,t-lymphocyte/analysisenglishabstractfemalehumanKWDhivseropositivityiga/analysisigg/analysisigm/analysismalemiddleageriskfactorssubstanceabuse/KWDimmunologyjournalarticle
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Copyright © 1988 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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