Retinal cotton-wool-like spots: a marker for AIDS? NLM AIDSLINE Important note: Information in this article was accurate in 1988. The state of the art may have changed since the publication date.

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Retinal cotton-wool-like spots: a marker for AIDS?

Compr Ther. 1988 Mar;14(3):41-4. Unique Identifier : AIDSLINE MED/88195296
Pivetti-Pezzi P; Tamburi S; D'Offizi GP; Mezzaroma I; Aiuti F; Istituto di Oftalmologia, Roma, Italy.

Abstract: The prognostic value of ocular manifestations and their correlation with immune changes in HIV-infected subjects (75 PGL, 23 ARC, and 17 AIDS) have been longitudinally studied with an average follow-up of one year (3 to 22 months). The most common ocular manifestations were retinal cotton-wool-like spots, observed in 58.8% of AIDS patients and in 76.9% of those with ocular involvement. Two of three ARC patients who showed cotton-wool-like spots developed PCP a few weeks after ophthalmoscopic examination. A close correlation between ocular changes and decrease of CD4+ lymphocytes was observed. In our opinion, these ocular manifestations are as useful an indicator as opportunistic infections or AIDS-related neoplasias in the prognosis of HIV infection.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/*DIAGNOSIS/ IMMUNOLOGY Adolescence Adult AIDS-Related Complex/COMPLICATIONS/DIAGNOSIS/IMMUNOLOGY Child Child, Preschool Female Follow-Up Studies Human Infant Leukocyte Count Male Prognosis Retinal Diseases/*DIAGNOSIS/ETIOLOGY/IMMUNOLOGY Support, Non-U.S. Gov't JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complications/KWDdiagnosis/immunologyadolescenceadultaids-relatedcomplex/complications/diagnosis/immunologychildchild,preschoolfemalefollow-upstudieshumaninfantleukocytecountmaleprognosisretinaldiseases/KWDdiagnosis/etiology/immunologysupport,non-uKWDsKWDgov'tjournalarticle
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M8880477

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