Anticardiolipin antibodies associated with HTLV-III infection. NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

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Anticardiolipin antibodies associated with HTLV-III infection.

Br J Haematol. 1987 Apr;65(4):495-8. Unique Identifier : AIDSLINE MED/87214070
Canoso RT; Zon LI; Groopman JE

Abstract: Anticardiolipin antibody levels were determined in 73 homosexual men. Thirty of these patients had acquired immunodeficiency syndrome (AIDS), 16 patients had the AIDS-related complex (ARC) and 27 were healthy. Antibodies to human T-lymphotropic virus type III (HTLV-III) were detected in all patients with AIDS and ARC and in 11 of the healthy homosexuals. Eight patients with positive fluorescent treponemal antibody absorption test were excluded from the study. High levels of IgG-anticardiolipin antibodies were present in 23 of the 28 patients with AIDS; 12 of the 14 with ARC; five of the 10 HTLV-III positive healthy homosexuals; and none of the 13 HTLV-III negative healthy homosexuals. High levels of IgM-ACA were detected only in four patients with AIDS. The IgG-anticardiolipin levels were higher in the HTLV-III positive patients than in the HTLV negative group (P = 0.013). None of the patients with anticardiolipin antibodies exhibited venous thrombosis.
Keywords: Acquired Immunodeficiency Syndrome/*IMMUNOLOGY Antibodies/*ANALYSIS AIDS-Related Complex/IMMUNOLOGY Cardiolipins/*IMMUNOLOGY Homosexuality Human IgG/ANALYSIS IgM/ANALYSIS Male Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDimmunologyantibodies/KWDanalysisaids-relatedcomplex/immunologycardiolipins/KWDimmunologyhomosexualityhumanigg/analysisigm/analysismalesupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
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M8790348

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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