Developmental abnormalities in children with acquired immunodeficiency syndrome (AIDS): a follow-up study. NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

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Developmental abnormalities in children with acquired immunodeficiency syndrome (AIDS): a follow-up study.

Int J Neurosci. 1987 Feb;32(3-4):661-7. Unique Identifier : AIDSLINE MED/87249448
Ultmann MH; Diamond GW; Ruff HA; Belman AL; Novick BE; Rubinstein A; Cohen HJ

Abstract: Developmental abnormalities in 16 pediatric patients with AIDS or AIDS-Related Complex (ARC) were previously described. Neurological deterioration was in evidence on follow-up in 9 of the children, 5 died since the original assessments were performed. Ten patients were reevaluated 14 months later by cognitive testing. Two showed greater progress than expected on the basis of earlier test results; 6 showed the expected level of developmental progress; and the remaining 2 showed regression in cognitive functioning. All patients who exhibited regression in their developmental course showed deterioration in their neurological examinations. Developmental progression was noted in some children who on follow-up serial examinations exhibited a clinically deteriorating neurological picture. Pediatric AIDS patients manifest variable neurodevelopmental courses. As a result, rehabilitative intervention services must be tailored to meet individual needs.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS AIDS-Related Complex/COMPLICATIONS Central Nervous System Diseases/*ETIOLOGY Child Child Development Disorders/*ETIOLOGY Child, Preschool Cognition Disorders/ETIOLOGY Dementia/ETIOLOGY Follow-Up Studies Human Infant Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsaids-relatedcomplex/complicationscentralnervoussystemdiseases/KWDetiologychildchilddevelopmentdisorders/KWDetiologychild,preschoolcognitiondisorders/etiologydementia/etiologyfollow-upstudieshumaninfantsupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
871030
M87A0368

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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