Transmission of human immunodeficiency virus from parents to only one dizygotic twin. NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Transmission of human immunodeficiency virus from parents to only one dizygotic twin.

J Clin Microbiol. 1987 Jun;25(6):1119-21. Unique Identifier : AIDSLINE MED/87251319
Park CL; Streicher H; Rothberg R

Abstract: The acquired immunodeficiency syndrome-related complex was identified in a mother and one of her nonidentical twins. Generalized lymphadenopathy was first noted in the infant at age 17 months, and that of the mother was incidentally discovered 6 months later. The father, who had had homosexual contacts before the conception of the twins, appeared to be in good health. No one in the family had constitutional symptoms or showed signs of opportunistic infection. Both parents and the patient had hypergammaglobulinemia, low T-helper-to-suppressor-cell ratio, and positive serum antibody to human immunodeficiency virus. Attempts to isolate the virus from all family members were unsuccessful. The twin brother was in good health with a normal immunologic profile and negative antibody to human immunodeficiency virus.
Keywords: Acquired Immunodeficiency Syndrome/GENETICS/IMMUNOLOGY/ *TRANSMISSION Adult Antibody Formation AIDS-Related Complex/IMMUNOLOGY/*TRANSMISSION Case Report *Diseases in Twins Female Human Immunity, Cellular Infant Male Pregnancy *Twins *Twins, Dizygotic JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/genetics/immunology/KWDtransmissionadultantibodyformationaids-relatedcomplex/immunology/KWDtransmissioncasereportKWDdiseasesintwinsfemalehumanimmunity,cellularinfantmalepregnancyKWDtwinsKWDtwins,dizygoticjournalarticle
871030
M87A0366

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1987. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1987. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .