Clinically uninvolved skin in AIDS: evidence of atypical dermal vessels similar to early lesions observed in Kaposi's sarcoma. Ultrastructural study in four patients. NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Clinically uninvolved skin in AIDS: evidence of atypical dermal vessels similar to early lesions observed in Kaposi's sarcoma. Ultrastructural study in four patients.

J Cutan Pathol. 1987 Jun;14(3):154-7. Unique Identifier : AIDSLINE MED/87280933
De Dobbeleer G; Godfrine S; Andre J; Ledoux M; De Maubeuge J

Abstract: The clinically uninvolved skin of 4 patients with well-developed AIDS was investigated by electron microscopy. All biopsy specimens had vascular abnormalities: protruding endothelial cells, vascular channels reduced to slits, gaps within the vascular walls, and extravasated erythrocytes. These features are similar to those described in early lesions of Kaposi's sarcoma. These findings suggest that blood vessels of the clinically uninvolved skin of AIDS patients are potential sites of Kaposi's sarcoma lesions.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/*PATHOLOGY Adult Blood Vessels/ULTRASTRUCTURE Case Report Endothelium/*ULTRASTRUCTURE Human Male Middle Age Sarcoma, Kaposi's/*BLOOD SUPPLY/ETIOLOGY Skin/*BLOOD SUPPLY/ULTRASTRUCTURE Skin Neoplasms/*BLOOD SUPPLY/ETIOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complications/KWDpathologyadultbloodvessels/ultrastructurecasereportendothelium/KWDultrastructurehumanmalemiddleagesarcoma,kaposi's/KWDbloodsupply/etiologyskin/KWDbloodsupply/ultrastructureskinneoplasms/KWDbloodsupply/etiologyjournalarticle
871130
M87B0349

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1987. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1987. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .