Acquired immunodeficiency syndrome and infection with hepatitis viruses in individuals abusing drugs by injection. NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Acquired immunodeficiency syndrome and infection with hepatitis viruses in individuals abusing drugs by injection.

Bull Narc. 1986 Jan-Jun;38(1-2):15-25. Unique Identifier : AIDSLINE MED/87050248
Novick DM; Khan I; Kreek MJ

Abstract: The abuse by injection of heroin or other drugs has long been associated with liver disease caused by hepatitis B virus (HBV) and other viruses. Increasingly severe hepatic and virological complications of parenteral drug abuse have been reported due to infection with new viruses or concomitant alcohol abuse. The hepatitis delta virus (HDV) can replicate and cause liver infection only in the presence of HBV; such infection in HBV carriers may cause rapidly progressive and clinically significant liver disease. Liver cirrhosis is frequently detected in parenteral drug abusers who have chronic infection with both HBV and HDV or who also abuse alcohol. More than one quarter of those persons with acquired immunodeficiency syndrome (AIDS) in the United States of America are homosexual or heterosexual males who are parenteral drug abusers. Existing evidence implicates parenteral drug abusers in the spread of hepatitis viruses and the retrovirus associated with AIDS to the general population. To cope with these serious problems the authors suggest that more intensive international co-operation is needed, particularly with a view to promoting data collection, research and the exchange of knowledge and experience on measures that have been effective in dealing with parenteral drug abuse and its complications.
Keywords: Acquired Immunodeficiency Syndrome/PREVENTION & CONTROL/ *TRANSMISSION Alcoholism/COMPLICATIONS/PREVENTION & CONTROL *Cocaine Delta Infection/PREVENTION & CONTROL/*TRANSMISSION Hepatitis B/PREVENTION & CONTROL/*TRANSMISSION Heroin Dependence/*COMPLICATIONS/PREVENTION & CONTROL Human Injections, Intravenous/ADVERSE EFFECTS Male Risk Substance Abuse/*COMPLICATIONS/PREVENTION & CONTROL Substance Dependence/*COMPLICATIONS/PREVENTION & CONTROL Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. United States JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/prevention&control/KWDtransmissionalcoholism/complications/prevention&controlKWDcocainedeltainfection/prevention&control/KWDtransmissionhepatitisb/prevention&control/KWDtransmissionheroindependence/KWDcomplications/prevention&controlhumaninjections,intravenous/adverseeffectsmalerisksubstanceabuse/KWDcomplications/prevention&controlsubstancedependence/KWDcomplications/prevention&controlsupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDunitedstatesjournalarticle
870330
M8730263

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1987. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1987. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .