[AIDS in children. Histopathologic study of 12 cases] NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

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[AIDS in children. Histopathologic study of 12 cases]

Ann Pathol. 1986;6(4-5):300-4. Unique Identifier : AIDSLINE MED/87128398
Nezelof C; Roth A; Blanche S; Barbey S

Abstract: The anatomo-clinical investigation of a series of 12 cases of AIDS in infants, over two years in Hopital des Enfants Malades (Paris) allows the following observations to be made: the frequency of materno-foetal contaminations (8/12); the relative shortness of the incubation period (3-6 months); the variable degree of the atrophy of the lymphoid tissues; the absence of vascular proliferation; the interest of demonstrating viral proteins associated with LAV virus (p 18) in imprecisely identifiable cells of lymphoid tissue; the severity of the thymic alterations, which are characterized less by a lymphocyte depletion than by a loss of the maturation of the epithelial tissue, which still preserves its hormone secretory properties.
Keywords: Acquired Immunodeficiency Syndrome/*PATHOLOGY/TRANSMISSION Blood Transfusion/ADVERSE EFFECTS Child Child, Preschool English Abstract Female Human Infant Lymph Nodes/PATHOLOGY Male Maternal-Fetal Exchange Pregnancy Thymus Gland/PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDpathology/transmissionbloodtransfusion/adverseeffectschildchild,preschoolenglishabstractfemalehumaninfantlymphnodes/pathologymalematernal-fetalexchangepregnancythymusgland/pathologyjournalarticle
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Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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