Nonbronchoscopic lung lavage for diagnosis of opportunistic infection in AIDS. NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

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Nonbronchoscopic lung lavage for diagnosis of opportunistic infection in AIDS.

Chest. 1987 Mar;91(3):319-22. Unique Identifier : AIDSLINE MED/87132536
Mann JM; Altus CS; Webber CA; Smith PR; Muto R; Heurich AE

Abstract: Thirty patients known to have or suspected of having acquired immunodeficiency syndrome (AIDS) were evaluated for opportunistic pulmonary infection using a double lumen lavage catheter (DLL). Lavage specimens obtained were cytocentrifuged and initially stained by the Papanicolaou technique as a means of rapid evaluation for Pneumocystis carinii. If no opportunistic organism was identified, the patient underwent further diagnostic investigations. In 18 patients receiving mechanical ventilatory support, the procedure was performed via the endotracheal tube. Twelve patients who were less severely ill underwent the procedure via the transnasal route. In 43 percent (13/30), opportunistic infections were diagnosed by DLL. Twelve had P carinii, one of whom had cytomegalovirus and another of whom had Herpes simplex viruses, and one with Toxoplasma gondii. Thus, the sensitivity for all opportunistic infections was 86 percent (12/14). The volume of fluid recovered averaged 93 percent of that instilled. There was no significant difference between prelavage and postlavage PaO2. In this group of patients, double lumen lavage obviated the need for more invasive and expensive procedures.
Keywords: Acquired Immunodeficiency Syndrome/*PATHOLOGY Catheterization Female Human Irrigation/INSTRUMENTATION Lung/*PATHOLOGY Male Opportunistic Infections/*PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDpathologycatheterizationfemalehumanirrigation/instrumentationlung/KWDpathologymaleopportunisticinfections/KWDpathologyjournalarticle
870630
M8760396

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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