Ultrastructural alterations and virus-like particles in lymph nodes of drug addicts with lymphadenopathy syndrome (LAS). NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

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Ultrastructural alterations and virus-like particles in lymph nodes of drug addicts with lymphadenopathy syndrome (LAS).

Pathol Res Pract. 1986 Dec;181(6):755-60. Unique Identifier : AIDSLINE MED/87175193
Schiaffino E; Bestetti-Bosisio M; Toia G; Onida L; Riboli P; Schmid C

Abstract: Lymph node biopsies from 16 cases of intravenous drug addicts with lymphadenopathy syndrome (LAS) have been examined at the electron microscope. The main ultrastructural alterations observed in the lymphocytes, dendritic reticulum cells and endothelial cells were tubulo-reticular structures (TRS), test tube and ring shaped forms (TRF) and nuclear pockets (NP). Images suggesting virus budding from lymphocytes and virus-like particles have also been found in 9 out of the 16 cases. The possibility to correlate the latter findings with a better knowledge of LAS evolution and prognosis is discussed.
Keywords: Adult AIDS-Related Complex/COMPLICATIONS/MICROBIOLOGY/*PATHOLOGY Female Human Hyperplasia Inclusion Bodies, Viral/*ULTRASTRUCTURE Lymph Nodes/MICROBIOLOGY/*ULTRASTRUCTURE Male Microscopy, Electron Substance Dependence/COMPLICATIONS JOURNAL ARTICLE

KWDadultaids-relatedcomplex/complications/microbiology/KWDpathologyfemalehumanhyperplasiainclusionbodies,viral/KWDultrastructurelymphnodes/microbiology/KWDultrastructuremalemicroscopy,electronsubstancedependence/complicationsjournalarticle
870730
M8770272

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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