HUMAN B LYMPHOCYTES NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

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HUMAN B LYMPHOCYTES

Leukocyte Typing II; 2:1-560 1986. Unique Identifier : AIDSLINE ICDB/87626843
Anonymous; No affiliation given

Abstract: Results from the human B lymphocyte portion of the Second International Workshop on Human Leukocyte Differentiation Antigens, held in Boston, Massachusetts, 17-20 September 1984, are presented. Studies employing the 52 B cell/leukemia panel antibodies are presented under the following headings: serological specificity of B cell/leukemia monoclonal antibodies (mAbs), biochemical analysis of antigens defined by the workshop B cell/leukemia panel, immunohistochemical analysis of B cell/leukemia panel mAbs, expression of B cell/leukemia panel on leukemias and lymphomas, and functional significance of human B cell/leukemia antigens. Topics include radioimmunobinding assay; lymphocyte differentiation antigens in immunodeficiency diseases; B cell differentiation; spontaneous mouse erythrocyte rosette formation; antibodies of normal and neoplastic lymphoid tissues and cell lines; mAb reactivity with follicular dendritic cells in tissue sections and with lymphoblastoid cell lines; anti-B cell mAbs in thymus, lymph node, and normal skin; phenotypes of B chronic lymphocytic leukemia (B-CLL) B cells established with mAbs; subclassification of leukemia using mAbs; heterogeneity of B-CLL cells defined by mAbs; characterization of Burkitt's lymphoma cell lines with mAbs; phenotypic changes occurring during in vitro activation of human splenic B lymphocytes; B lymphocyte surface antigens involved in the regulation of immunoglobulin secretion; detection of interleukin-2 receptors on activated human B cells; receptors for Epstein-Barr virus; mAb-defined surface molecules and their regulation of lymphocyte activation; and platelet aggregation inhibition by Fab monomers of mAb BA-2.
Keywords: Antibodies, Monoclonal/*IMMUNOLOGY Antigens, Surface/*ANALYSIS Human Leukocytes/*IMMUNOLOGY MONOGRAPH

KWDantibodies,monoclonal/KWDimmunologyantigens,surface/KWDanalysishumanleukocytes/KWDimmunologymonograph
870228
M8720254

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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