Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.
[Gastrointestinal manifestations of acquired immunodeficiency syndrome; case studies of 14 patients]
Schweiz Med Wochenschr. 1986 Oct 4;116(40):1358-66. Unique Identifier : AIDSLINE MED/87042708 Bengoa JM; Widgren S
Abstract:
The gastrointestinal manifestations seen in acquired immune deficiency syndrome (AIDS) are discussed based on the observation of 14 patients with a positive serology for LAV/HTLV III antibody. AIDS was confirmed in 8 cases and AIDS related complex (ARC) in 6 cases. Risk groups included 6 homosexuals, 6 drug abusers and 2 patients from Zaire. All the AIDS cases underwent gastrointestinal endoscopy and biopsy; in 5 patients a necropsy was performed. Evaluation of the immune status showed lymphopenia and a decreased ratio of OKT4/OKT8. Clinical and pathological observations are discussed sequentially. Acute esophagitis includes cases of Candida albicans super-infection, cytomegalovirus and herpes simplex. Acute enteritis and colitis were seen in association with cryptosporidium, Isospora belli and CMV. 3 cases were found to have chronic duodenitis and malabsorption. Digestive lesions of Kaposi's sarcoma were seen in 3 cases. Diagnosis and treatment of gastrointestinal infections in AIDS is important in view of the high morbidity and serious secondary complications.
Keywords: Acquired Immunodeficiency Syndrome/*PATHOLOGY Adult Colitis/PATHOLOGY Duodenitis/PATHOLOGY English Abstract Enteritis/PATHOLOGY Esophagitis/PATHOLOGY Female Gastrointestinal Diseases/*PATHOLOGY Human Male Middle Age Pancreatitis/PATHOLOGY Sarcoma, Kaposi's/PATHOLOGY JOURNAL ARTICLE
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