Incidence and mechanism of neutropenia and thrombocytopenia in patients with human immunodeficiency virus infection. NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

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Incidence and mechanism of neutropenia and thrombocytopenia in patients with human immunodeficiency virus infection.

Br J Haematol. 1987 Jul;66(3):337-40. Unique Identifier : AIDSLINE MED/87299489
Murphy MF; Metcalfe P; Waters AH; Carne CA; Weller IV; Linch DC; Smith A

Abstract: The incidence of lymphopenia, thrombocytopenia and neutropenia was studied in 105 homosexual men with HIV infection. Lymphopenia was common in patients with AIDS (75%), but its incidence in PGL (24%) was not significantly different from that in asymptomatic anti-HIV positive (15%) homosexual men. Neutropenia and thrombocytopenia were found in patients with AIDS or PGL, but not in asymptomatic anti-HIV positive homosexuals. The study suggests that the neutropenia and thrombocytopenia in these patients were due to autoimmune destruction of neutrophils and platelets.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Agranulocytosis/*ETIOLOGY Homosexuality Human Lymphatic Diseases/COMPLICATIONS Lymphopenia/ETIOLOGY Male Neutropenia/*ETIOLOGY Support, Non-U.S. Gov't Thrombocytopenia/*ETIOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsagranulocytosis/KWDetiologyhomosexualityhumanlymphaticdiseases/complicationslymphopenia/etiologymaleneutropenia/KWDetiologysupport,non-uKWDsKWDgov'tthrombocytopenia/KWDetiologyjournalarticle
871230
M87C0355

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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