Pulmonary manifestations of Kaposi's sarcoma. NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

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Pulmonary manifestations of Kaposi's sarcoma.

Chest. 1987 Jan;91(1):39-43. Unique Identifier : AIDSLINE MED/87079785
Garay SM; Belenko M; Fazzini E; Schinella R

Abstract: Pulmonary Kaposi's sarcoma is an unusual pre-mortem diagnosis in AIDS patients. During a four-year period, 318 patients with AIDS-associated Kaposi's sarcoma presented to New York University Medical Center; 19 patients were found to have pulmonary involvement. All 19 patients were homosexual men; 18 of these patients presented with cutaneous and/or visceral Kaposi's sarcoma. Seventy-nine percent of patients had previous or concurrent pulmonary opportunistic infections. Clinical presentation of pulmonary Kaposi's sarcoma was indistinguishable from opportunistic pneumonia with respect to symptoms, physical examination results, and laboratory findings. Chest roentgenograms revealed a typical nodular pattern in only five patients. In contrast to AIDS-associated opportunistic pneumonia, the yield from fiberoptic bronchoscopy (24 percent) and open lung biopsy (56 percent) was low. Pathologically, Kaposi's sarcoma of the lung is less cellular than the cutaneous lesion. It is focal and scattered throughout the pulmonary interstitium, which may explain the difficulty in pre-mortem diagnosis.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Bronchoscopy Homosexuality Human Male Middle Age Opportunistic Infections/COMPLICATIONS/DIAGNOSIS/PATHOLOGY Retrospective Studies Sarcoma, Kaposi's/*COMPLICATIONS/DIAGNOSIS/PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultbronchoscopyhomosexualityhumanmalemiddleageopportunisticinfections/complications/diagnosis/pathologyretrospectivestudiessarcoma,kaposi's/KWDcomplications/diagnosis/pathologyjournalarticle
870430
M8740257

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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