[AIDS in a woman having had sexual relations with a patient with hemophilia A. Characteristic findings in DNA image cytometry] NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

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[AIDS in a woman having had sexual relations with a patient with hemophilia A. Characteristic findings in DNA image cytometry]

Dtsch Med Wochenschr. 1986 Dec 19;111(51-52):1966-9. Unique Identifier : AIDSLINE MED/87080041
Schaar H; Auffermann W; Bocking A; Franke P; Pusztai-Markos Z; Reininghaus A; Schmitt H

Abstract: A 37-year-old female patient reported marked weight loss, prolonged alopecia, recurrent infections and watery diarrhoea. Examination revealed Salmonella infection, candidiasis and immunological signs of previous toxoplasmosis. Between 1978 and 1981, the patient had had close sexual relations to a patient with haemophilia A. Due to this fact, AIDS was suspected. Serological tests for HIV were not available at the time. The findings in DNA image cytometry (nuclear DNA inclusion bodies, polyploid lymphocyte nuclei and binuclear lymphocytes) suggested a viral infection of the lymphoid cells. Electron microscopy revealed in hepatocytes and cerebral cells intranuclear inclusion bodies whose size and contents were not compatible with an infection caused by cytomegalovirus, herpes virus or Epstein-Barr virus. In autopsy, infections of various organ systems such as pneumonia, tracheobronchitis, urocystitis, pyelonephritis, Candida oesophagitis and enteritis were found.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/DIAGNOSIS/ *TRANSMISSION Adult Case Report DNA/ANALYSIS English Abstract Female Flow Cytometry Hemophilia/*PHYSIOPATHOLOGY Human Inclusion Bodies, Viral/ULTRASTRUCTURE Opportunistic Infections/ETIOLOGY *Sex JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complications/diagnosis/KWDtransmissionadultcasereportdna/analysisenglishabstractfemaleflowcytometryhemophilia/KWDphysiopathologyhumaninclusionbodies,viral/ultrastructureopportunisticinfections/etiologyKWDsexjournalarticle
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M8740256

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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