Neuropathology of acquired immunodeficiency syndrome (AIDS). Analysis of 22 Brazilian cases. NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Neuropathology of acquired immunodeficiency syndrome (AIDS). Analysis of 22 Brazilian cases.

J Neurol Sci. 1986 Dec;76(2-3):187-98. Unique Identifier : AIDSLINE MED/87085675
Rosemberg S; Lopes MB; Tsanaclis AM

Abstract: The neuropathologic study of 22 Brazilian cases of acquired immuno-deficiency syndrome (AIDS) was performed. Thirteen cases (59%) showed neuropathologic lesions. These included infection by Toxoplasma (n = 4), Cryptococcus neoformans (n = 3), viral encephalitis (n = 4), primary lymphomas (n = 2), isolated cerebral infarct (n = 1), and reactive gliosis (n = 1). In 2 cases, primary lymphoma and viral encephalitis were associated. Axonal spheroids in the gracilis and cuneatus nuclei were present in a case of toxoplasmosis. Mammillary bodies lesions consistent with Wernicke's encephalopathy were found in a case of viral encephalitis. In addition, circulatory changes (focal cortical infarcts) were associated lesions in 3 cases. These findings were compared with the main series reported in American and European literature.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS/EPIDEMIOLOGY Adolescence Adult Brain/*PATHOLOGY Brain Abscess/ETIOLOGY/PATHOLOGY Brain Diseases/ETIOLOGY/*PATHOLOGY Brain Neoplasms/ETIOLOGY/PATHOLOGY Brazil Cryptococcosis/PATHOLOGY Human Lymphoma/ETIOLOGY/PATHOLOGY Male Middle Age Toxoplasmosis/PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplications/epidemiologyadolescenceadultbrain/KWDpathologybrainabscess/etiology/pathologybraindiseases/etiology/KWDpathologybrainneoplasms/etiology/pathologybrazilcryptococcosis/pathologyhumanlymphoma/etiology/pathologymalemiddleagetoxoplasmosis/pathologyjournalarticle
870430
M8740234

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1987. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1987. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .