Bone marrow findings in acquired immunodeficiency syndrome (AIDS). NLM AIDSLINE Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.

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Bone marrow findings in acquired immunodeficiency syndrome (AIDS).

Am J Med Sci. 1986 Dec;292(6):372-5. Unique Identifier : AIDSLINE MED/87097411
Shenoy CM; Lin JH

Abstract: Bone marrow aspirates and biopsies from 35 AIDS/AIDS-related complex patients, consisting primarily of intravenous drug abusers, were studied. The most common findings included hypercellularity (86%), plasmacytosis (63%), reticular fibrosis (50%), and lymphocytosis (37%) occasionally admixed with histiocytes. Granulocytic hyperplasia was present in 27 patients (77%). Erythrocytic hypoplasia was observed in 15 patients (43%). Megaloblastic changes of intermediate form were seen in two cases and serous fat atrophy was noted in another three patients. One M. tuberculosis granuloma, a foreign body granuloma and two granulomas of undetermined etiology were seen, each in separate patients. A previously unreported focal vascular proliferation was seen in one case. The majority of cases showed increased stainable iron. Some of our findings are at variance with previous reports. This may reflect differences in patient population, geographic distribution, risk factors and epidemiologic mode in our cases.
Keywords: Acquired Immunodeficiency Syndrome/*PATHOLOGY Adult Biopsy, Needle Bone Marrow/ANALYSIS/CYTOLOGY/*PATHOLOGY Erythrocytes/PATHOLOGY Female Granulocytes/PATHOLOGY Granuloma/PATHOLOGY Human Hyperplasia Iron/ANALYSIS Lymphocytosis/PATHOLOGY Male Megakaryocytes/PATHOLOGY Middle Age JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDpathologyadultbiopsy,needlebonemarrow/analysis/cytology/KWDpathologyerythrocytes/pathologyfemalegranulocytes/pathologygranuloma/pathologyhumanhyperplasiairon/analysislymphocytosis/pathologymalemegakaryocytes/pathologymiddleagejournalarticle
870430
M8740206

Copyright © 1987 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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