Exercise P-vector magnitude changes in angina pectoris: Frank-Vectorcardiographic and hemodynamic correlations.

Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

Exercise P-vector magnitude changes in angina pectoris: Frank-Vectorcardiographic and hemodynamic correlations.

J Electrocardiol. 1986 Apr;19(2):115-21. Unique Identifier : AIDSLINE MED/86225900
Yokota M; Jing HX; Takagi S; Tsunekawa A; Koide M; Iwase M; Tsuzuki M; Yoshida R; Sotobata I

Abstract: Multistage bicycle ergometer exercise testings with Frank vectorcardiogram and M-mode echocardiogram were performed on 12 patients with effort angina pectoris. The left atrial and left ventricular end-diastolic volume (LAV and LVEDV) were calculated as a cube of the left atrial and left ventricular end-diastolic dimension. The mean pulmonary artery wedge pressure (mPAWP) was measured with a Swan-Ganz catheter during the testing. At peak exercise a statistically significant increase was observed in mPAWP (p less than 0.001), LAV (p less than 0.005), the maximal horizontal P-vector magnitude (Hmax) (p less than 0.05) and the percent change in Hmax (%Hmax). %Hmax showed a significant correlation with the increment of mPAWP (delta mPAWP) (r = 0.66, p less than 0.05), the increment of LVEDV (delta LVEDV) (r = 0.83, p less than 0.01) and the increment of LAV (delta LAV) (r = 0.81, p less than 0.001). Multiple regression analysis was performed on %Hmax as a dependent variable with delta LAV, delta mPAWP, and the increment of heart rate (delta HR) as independent variables (r = 0.84, p less than 0.05), but the partial correlation coefficients of delta mPAWP and delta HR were not significant. The present study demonstrated that the increase in Hmax had a close relationship with the increase in mPAWP and LVEDV and that the preload of the left ventricle during exercise-induced anginal attack could be predicted noninvasively by %Hmax. The increase in Hmax was thought to be due to the increase in LAV during anginal attack.

Keywords: Adult Angina Pectoris/*DIAGNOSIS/PHYSIOPATHOLOGY Coronary Disease/*DIAGNOSIS/PHYSIOPATHOLOGY Coronary Vessels/RADIOGRAPHY Echocardiography/METHODS *Exercise Test Female Heart Conduction System/PHYSIOPATHOLOGY *Hemodynamics Human Male Middle Age Myocardial Contraction Vectorcardiography/*METHODS JOURNAL ARTICLE

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