Kaposi's sarcoma with bone marrow involvement: occurrence in a patient with the acquired immunodeficiency syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Kaposi's sarcoma with bone marrow involvement: occurrence in a patient with the acquired immunodeficiency syndrome.

Am J Med Sci. 1986 Jul;292(1):44-6. Unique Identifier : AIDSLINE MED/86239326
Little BJ; Spivak JL; Quinn TC; Mann RB

Abstract: A patient with the acquired immune deficiency syndrome (AIDS) and the lymphadenopathic variant of Kaposi's sarcoma developed skin, gastrointestinal and pulmonary lesions. A cellular specimen was obtained on bone marrow aspiration, but the bone marrow biopsy revealed dense reticulin fibrosis with slit-like spaces and endothelial-lined channels consistent with Kaposi's sarcoma. At postmortem examination, Kaposi's sarcoma was found in the pleura and lungs, throughout the gastrointestinal tract, in the liver and spleen, and in the thoracic and abdominal lymph nodes. Bone marrow architecture appeared grossly normal, but microscopic examination revealed numerous foci of Kaposi's sarcoma. This is the first reported example of bone marrow involvement with Kaposi's sarcoma in AIDS recognized antemortem.
Keywords: Abdominal Neoplasms/ETIOLOGY/PATHOLOGY Acquired Immunodeficiency Syndrome/*COMPLICATIONS/PATHOLOGY Adult Bone Marrow/*PATHOLOGY Case Report Gastrointestinal Neoplasms/ETIOLOGY/PATHOLOGY Homosexuality Human Lung Neoplasms/*ETIOLOGY/PATHOLOGY Lymphatic Metastasis Male Respiratory Insufficiency/ETIOLOGY Sarcoma, Kaposi's/*ETIOLOGY/PATHOLOGY Thoracic Neoplasms/ETIOLOGY/PATHOLOGY JOURNAL ARTICLE

KWDabdominalneoplasms/etiology/pathologyacquiredimmunodeficiencysyndrome/KWDcomplications/pathologyadultbonemarrow/KWDpathologycasereportgastrointestinalneoplasms/etiology/pathologyhomosexualityhumanlungneoplasms/KWDetiology/pathologylymphaticmetastasismalerespiratoryinsufficiency/etiologysarcoma,kaposi's/KWDetiology/pathologythoracicneoplasms/etiology/pathologyjournalarticle
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M8690189

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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