Bronchoalveolar lavage in patients with the acquired immune deficiency syndrome (AIDS). NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Bronchoalveolar lavage in patients with the acquired immune deficiency syndrome (AIDS).

AIDS Res. 1983-84;1(2):91-7. Unique Identifier : AIDSLINE MED/86242453
Baughman RP; Solinger A; Hurtubise P; Dohn MN; Walzer PD; Rashkin MC; Dortin D

Abstract: The lymphocytes retrieved by bronchoalveolar lavage (BAL) of three patients with the acquired immune deficiency syndrome were studied to determine the local immune status of these patients. These results were compared to those of patients with pulmonary sarcoidosis, who have similar systemic immune response (anergy, hypergammaglobulinemia). In these AIDS patients, the T4/T8 ratio in the BAL was 0.44 +/- 0.20. In eleven patients with pulmonary sarcoidosis, the bronchoalveolar lavage showed a T4/T8 ratio of 7.51 +/- 2.14. It is possible that patients with AIDS are unable to change the local immune response in the lung and thus are at risk for unusual infections.
Keywords: Acquired Immunodeficiency Syndrome/IMMUNOLOGY/*PATHOLOGY Bronchi/*PATHOLOGY Comparative Study Human Irrigation Lung Diseases/IMMUNOLOGY/PATHOLOGY Lymphocytes/*PATHOLOGY Male Pulmonary Alveoli/*PATHOLOGY Sarcoidosis/IMMUNOLOGY/PATHOLOGY Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. T-Lymphocytes/CLASSIFICATION JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/immunology/KWDpathologybronchi/KWDpathologycomparativestudyhumanirrigationlungdiseases/immunology/pathologylymphocytes/KWDpathologymalepulmonaryalveoli/KWDpathologysarcoidosis/immunology/pathologysupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes/classificationjournalarticle
861030
M86A0311

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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