Biochemical, hematologic, and histopathologic studies in rabbits intrarectally inseminated. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Biochemical, hematologic, and histopathologic studies in rabbits intrarectally inseminated.

AIDS Res. 1983-84;1(5):299-307. Unique Identifier : AIDSLINE MED/86242461
Wicher V; Wicher K; Gruhn R; Pragay DA; Durham S; Gould MC

Abstract: Rabbits subjected three times a week for 7 months to administrations of fresh homologous semen, colonic enemas, or semen (previously frozen at -70 degrees) preceded by enema were monitored by a battery of biochemical and hematologic tests and histopathologic examination. No biochemical, hematologic or histopathologic changes were observed. Negative blood cultures and serum endotoxin determinations excluded any possibility of systemic bacterial infection caused or induced by the treatments. Wide temporary variations in the hematologic parameters, including concentrations of T and B cells, were observed in all treated groups. The relevance of these findings to immune status is not yet certain.
Keywords: Animal B-Lymphocytes/CYTOLOGY Blood Bactericidal Activity Blood Chemical Analysis Colon/PATHOLOGY Disease Models, Animal Endotoxins/BLOOD *Enema Hematologic Tests *Insemination Irrigation/METHODS Male Rabbits Support, U.S. Gov't, P.H.S. T-Lymphocytes/CYTOLOGY JOURNAL ARTICLE

KWDanimalb-lymphocytes/cytologybloodbactericidalactivitybloodchemicalanalysiscolon/pathologydiseasemodels,animalendotoxins/bloodKWDenemahematologictestsKWDinseminationirrigation/methodsmalerabbitssupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes/cytologyjournalarticle
861030
M86A0309

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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