Transfusion induced acquired immunodeficiency syndrome (AIDS) with Kaposi's sarcoma in a patient with congenital factor V deficiency. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Transfusion induced acquired immunodeficiency syndrome (AIDS) with Kaposi's sarcoma in a patient with congenital factor V deficiency.

AIDS Res. 1984-85;1(6):401-6. Unique Identifier : AIDSLINE MED/86242471
Velez-Garcia E; Fradera J

Abstract: The first instance ever reported of transfusion induced AIDS with Kaposi's sarcoma in a non-homosexual patient is presented in detail. Our experience in this case supports the theory that a transfusion induced viral agent or agents which may affect the immunoregulatory mechanism could be the underlying cause. The rarity of patients such as ours suggests that other, so far undescribed, factors must be playing an essential role in the development of this rare form of cancer in high risk groups represented by patients with AIDS. Further studies are needed to ascertain the mechanisms whereby the different expressions of this syndrome are manifested in such patients.
Keywords: Acquired Immunodeficiency Syndrome/*ETIOLOGY/TRANSMISSION Adult Blood Transfusion/*ADVERSE EFFECTS Case Report Factor V Deficiency/CONGENITAL/*COMPLICATIONS Histocompatibility Antigens Class II/ANALYSIS Human Lymphocyte Transformation/DRUG EFFECTS Male Sarcoma, Kaposi's/*COMPLICATIONS Support, U.S. Gov't, P.H.S. T-Lymphocytes, Cytotoxic/IMMUNOLOGY T-Lymphocytes, Helper-Inducer/IMMUNOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDetiology/transmissionadultbloodtransfusion/KWDadverseeffectscasereportfactorvdeficiency/congenital/KWDcomplicationshistocompatibilityantigensclassii/analysishumanlymphocytetransformation/drugeffectsmalesarcoma,kaposi's/KWDcomplicationssupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes,cytotoxic/immunologyt-lymphocytes,helper-inducer/immunologyjournalarticle
861030
M86A0300

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1986. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1986. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .